To determine the effect of glucocorticoids on EGFR/STAT3 signaling in anti-GBM nephritis, we performed immunohistochemical staining of phosphorylated EGFR and STAT3 in the renal biopsies of the patients with (n = 22) and without (n = 12) glucocorticoids treatment. The gene discussed is STAT3; the disease is nephritis.