NOS2 and neoplasm: Moreover, we plotted the correlation between ITGB5 expression and gene markers of macrophage, and the ITGB5 expression was significantly correlated with macrophage markers, including M1 macrophages markers (NOS2, IL1B, CD86), M2 macrophages markers (CSF1R, MRC1, CD163), and tumor-associated macrophage markers (MARCO, CSF1R, CD40) (Figures 13A–C).