Besides, we further evaluated the expression situation and proportion of immune cells in CYP1B1-related groups from IDD patients, and results indicated that in blood tissues of IDD patients, neutrophils, monocytes, T cells CD4 memory resting, and γδT cells were dominant, while eosinophils, mast cells resting, dendritic cells resting were hardly existed (Figure 6F). This evidence concerns the gene CD4 and intervertebral disk degenerative disorder.