As shown in Figures 6C,D, GSEA results indicated that “type I diabetes mellitus”, “DNA replication”, “graft versus host disease”, “herpes simplex virus I infection”, and “allograft rejection”, etc were enriched in CYP1B1-low group, while “neutrophil extracellular trap formation”, “osteoclast differentiation”, “Fc gamma R-mediated phagocytosis”, “transcriptional mis-regulation in cancer”, etc were enriched in CYP1B1-high group, which contained several immune-related pathways. The gene discussed is CYP1B1; the disease is cancer.