GNPAT and Intellectual disability: Genetic mutation of two major peroxisomal enzymes related to Pls synthesizing enzymes, glyceronephosphate O-acyltransferase (GNPAT) and alkylglycerone phosphate synthase (AGPS), and their modulator Pex-7 has been found in Rhizomelic Chondrodysplasia Punctata (RCDP), which is a disorder characterized by developmental problems, congenital contractures, and severe intellectual disability (Braverman and Moser, 2012; Itzkovitz et al., 2012).