miR-185-5p targets ROCK2 (Niu and Tang, 2019), ELK1 (Fan et al., 2018), ELK3 (Liu et al., 2020), IGF2 (Zhuang et al., 2020), RAGE (Yin et al., 2018), BCL2, BCL2L1 (Ostadrahimi et al., 2018), and many other genes to suppress tumor cell migration and invasion. Here, IGF2 is linked to neoplasm.