miR-185-5p targets ROCK2 (Niu and Tang, 2019), ELK1 (Fan et al., 2018), ELK3 (Liu et al., 2020), IGF2 (Zhuang et al., 2020), RAGE (Yin et al., 2018), BCL2, BCL2L1 (Ostadrahimi et al., 2018), and many other genes to suppress tumor cell migration and invasion. The gene discussed is ROCK2; the disease is neoplasm.