In salivary adenoid cystic carcinoma (SACC), NT-3/TrkC signaling enhances in-vitro cancer cell migration in the presence of Schwann cells: A comparative study of 78 SACC and 25 normal tissue specimens demonstrated higher expression of NT-3 in tumor cells surrounding the nerves and TrkC in tumor-invaded nerves; statistics proved that level of NT-3/TrkC expression is strongly correlated with the occurrence of PNI (Li et al., 2019). The gene discussed is NTF3; the disease is cancer.