AKT1 and cancer: In addition, several STAR signaling pathways were found to be associated with oncogenesis, such as the PI3K–Akt signaling pathway (p = 0.00017), Notch signaling pathway (p = 0.0078), transcriptional misregulation in cancer (p = 0.021), and Hippo signaling pathway (p = 0.042) (Figure 9E).