STX1A and hemolytic-uremic syndrome: In a different approach, immunoglobulin-rich bovine colostrum preparation containing a high titer of anti-Stx1 and anti-Stx 2 was tested in patients; however, the treated patient did not show a significant difference compared with the placebo-treated patient; also, HUS development or other possible infection complications were not analyzed by study subjects (Huppertz et al., 1999).