GSTM1 and sarcopenia: As is shown in Table 4, age ≥60 years (P <0.001), Hb <100g/L (P = 0.077), ELN intermediate risk (P = 0.068), ELN high risk (P = 0.002), sarcopenia (P = 0.004), frailty of G-8 (P = 0.001) and reduced-intensity regimens (P <0.001) were inferior prognostic factors, and HCT-CI score of 1–2 was a superior prognostic factor for OS in univariate analysis.