Based on the bioinformatic analysis of the datasets from The Cancer Genome Atlas (TCGA, https://www.cancer.gov/tcga) database (27), we found that NEK7 expression was highly correlated with expression levels of Kras and GSDMD in HCC tumor tissues (Figures 1F, G and S1B). The gene discussed is GSDMD; the disease is hepatocellular carcinoma.