To explore the relationship between the expression of AFF4 and the prognosis of colorectal cancer patients, we collected RNA sequencing data from TCGA database and the Human Protein Atlas database, respectively (Supplemental Figures 1B, C), and analyzed the correlation of low expression of AFF4 and the survival time of colorectal cancer patients by Kaplan-Meier. The gene discussed is AFF4; the disease is colorectal cancer.