In terms of tumor-promoting effects, propofol has been found to increase the migration of breast cancer cells in association with the activation of the γ-aminobutyric acid type A receptor (65), and to promote the proliferation and migration of human breast cancer cells in association with the inhibition of p53 and activation of nuclear factor E2–related factor-2 in vitro (66). Here, TP53 is linked to neoplasm.