IL18 and acute kidney injury: The AUC-ROC analysis showed that sIL-18 and uIL-18 could be used as moderate biomarkers to predict AKI in preterm infants, in line with Parikh et al.(2006) [36] and Wang et al. (2017) [37], who reported that IL-18 level can be used as an early biomarker and prognosis for AKI [31,32].