These include Prime time entertainment network (PTEN), metadherin (MTDH), cell division protein kinase 6 (CDK6), enhancer of zeste homolog 2 (EZH2), myeloid cell leukemia 1 (MCL-1), Pyruvate Dehydrogenase Complex Component X (PDHX), Chromodomain-helicase-DNA-binding protein 1(CHD1), Growth regulation by estrogen in breast cancer 1 (GREB1), and Karyopherin Alpha 2 (KPNA2) [33,44]. This evidence concerns the gene PDHX and cancer.