AKT1 and cancer: Kongtawelert et al. conducted the antibreast cancer activities of sesamin and reported that sesamin (0-200 μM) inhibited cell proliferation with suppressing metastasis by the inactivation of oncosignaling pathways like P13K/AKT, NF-κB, ERK, and JAK/STAT in MDA-MB 321 cell lines [69].