Another previous research regarding human beta defensin-6 (hBD-6) found that hBD-6 with microvesicles shed by breast cancer cell lines can physically interact with peptides derived from the extracellular domain of CC chemokine receptor 2 (CCR2), indicating that defensins present the chemoattractive activity by interacting with chemokine receptor [36]. The gene discussed is CCR2; the disease is breast carcinoma.