IL1B and acute respiratory distress syndrome: Previous research discovered that the herbal compound could alleviate and provide a protective effect on lung tissue injury of LPS-induced ARDS rats, reduce exudation of inflammatory cells, inhibit key proinflammatory cytokine interleukin-1β (IL-1β), and could lower protein expression of nuclear transcription factor -κB (NF-κB) p50, p65, and mitogen-activated protein kinase p38 (p38 MAPK) on the inflammatory pathway [7].