The mean value of the CD4+ count was 303.08, which is an indication of a chronic co-infection of HCV/HIV since the patients have been on antiretroviral drugs for not less than 6 months, and should have begun to have an increase in their CD4 count, as observed by the McGovern et al. 19 in which he stated that HCV has a negative impact on the restoration of the CD4 count, which is associated with liver cirrhosis. This evidence concerns the gene CD4 and cirrhosis of liver.