Overall, our pan-cancer analysis of ALKBH7 is the first to explore the relationship between ALKBH7 expression in human cancers and clinical prognostic factors, immune subtypes, molecular subtypes, immune checkpoints (ICPs), tumor mutational burden (TMB), microsatellite instability (MSI), tumor stemness index, tumor microenvironment (TME) and tumor-infiltrating lymphocytes (TILs). The gene discussed is ALKBH7; the disease is cancer.