Consequently, low FAM46C expression was observed in eight tumours: bladder uroepithelial carcinoma (BLCA), colon adenocarcinoma (COAD), oesophageal cancer (ESCA), kidney chromophobe (KICH), prostate adenocarcinoma (PRAD), rectal adenocarcinoma (READ), stomach adenocarcinoma (STAD) and thyroid carcinoma (THCA) (Figure 1B). This evidence concerns the gene TENT5C and bladder transitional cell carcinoma.