CHD2 and early-infantile DEE: Interestingly, the ages of seizure onset of patients who were seizures control and carried CHD2 non-CNVs were from 1 to 12 years, and generalized tonic-clonic seizures (GTCS, 61.1%, 11/18) and myoclonic seizures (MS, 38.9%, 7/18) were the top two seizure types (Supplementary Table S1).