The qRT-PCR results showed that compared with the normal renal tissues, the expression level of EPO, PLAUR, TGFA and TGFB1 were higher in the ccRCC tissue, while the expression level of TEK were lower, trends in the expression levels of these genes were consistent with our findings (Figure 11). The gene discussed is TGFB1; the disease is nonpapillary renal cell carcinoma.