Moreover, the expression of PLAGL2 was associated with the expression of markers of specific subsets of T cells in GBM, which included the Th1 marker, TBX2 (r = 0.407, p < 0.001); Th2 marker, CD14 (r = 0.171, p < 0.05), GATA3 (r = 0.177, p < 0.05), STAT6 (r = 0.265, p < 0.01), STAT5A (r = 0.43; p < 0.001); Tfh marker, BCL6 (r = 0.444, p < 0.001); Th17 marker, STAT3 (r = 0.608, p < 0.001); Treg marker, FOXP3 (r = 0.231, p < 0.01), STAT5B (r = 0.612, p < 0.001), and TGFB (r = 0.363, p < 0.001). The gene discussed is STAT3; the disease is glioblastoma.