As shown in Figure 6A, PLAGL2 was positively associated with purity (rho = 0.265, p = 0.0017), B cells (rho = 0.178, p = 0.0371), CD4+T cells (rho = 0.335, p < 0.001), macrophages (rho = 0.231, p < 0.01), neutrophils (rho = 0.461, p < 0.001) and DCs (rho = 0.428, p < 0.001), and negatively associated with CD8+T cells (rho = -0.314, p < 0.001) in GBM. The gene discussed is CD4; the disease is glioblastoma.