The genes responsible for this association were likely PDE3A, which had a nominal association with COVID-19 positivity (p = 0.018), and IGF1, for which we were underpowered to detect an association with COVID-19 hospitalization in our study (p = 0.14) but which has been implicated in previous COVID-19 studies (Fan et al., 2021). This evidence concerns the gene IGF1 and COVID-19.