For variants located exactly within the gene(s), significant immunologically relevant associations were found for CTCF (eosinophil WBC count), MAU2 (basophil WBC count), PDS5B (asthma), SGOs (multiple sclerosis, IgG glycosylation, macrophage driven inflammation), SMC1B (RA), STAG1 (RA, lymphocyte cell count, C-reactive protein levels). The gene discussed is CRP; the disease is rheumatoid arthritis.