Indeed, this selection of immunologically relevant traits was enriched in other SNPs associated with lymphocyte counts, asthma and lung function, C-reactive protein levels, RA and, included a set of chronic inflammatory diseases traditionally associated with the genetic HLA-B27 background including ankylosing spondylitis, Crohn’s disease, psoriasis, primary sclerosing cholangitis, and ulcerative colitis. This evidence concerns the gene CRP and asthma.