Ebrahimi et al. (110)found that the levels of rheumatoid factor(RF), erythrocyte sedimentation rate(ESR), C-reactive protein(CRP), and anti-cyclic peptide containing citrulline (anti-CCP) antibody within RA patients with H. pylori are obviously higher than those in RA patients without H. pylori infection. The gene discussed is CRP; the disease is rheumatoid arthritis.