TNFRSF1A and idiopathic pulmonary fibrosis: In this context, the transcriptional levels of pro-apoptotic (BID and DIABLO) and anti-apoptotic (Bcl-2 and Mcl-1), which are related to the intrinsic pathway of apoptosis, as well as TNFR1, which is involved in the extrinsic pathway, were evaluated in T cells after 3 and 24 h of culture with IPF (SN) and CLF (SN) (Figure 4).