Indeed, enhanced levels of CCR1 and/or CCR5 were shown to be present on monocytes from hemolytic uremic syndrome (HUS) or chronic obstructive pulmonary disease (COPD) patients, even though HUS or COPD monocytes did not respond as well as monocytes from healthy individuals in functional assays (21, 22). The gene discussed is CCR1; the disease is chronic obstructive pulmonary disease.