Indeed, enhanced levels of CCR1 and/or CCR5 were shown to be present on monocytes from hemolytic uremic syndrome (HUS) or chronic obstructive pulmonary disease (COPD) patients, even though HUS or COPD monocytes did not respond as well as monocytes from healthy individuals in functional assays (21, 22). The gene discussed is CCR5; the disease is hemolytic-uremic syndrome.