IL1R1 and neoplasm: We observed that highly expressed genes in myeloid cells in tumors with a high TIL score are indicative of their polarization towards a classically activated phenotype, e.g., CTSS, FcER1G, PLAUR, CYBB, and PTPRC (45–49), while the genes that were highly expressed in myeloid cells in tumors with low TIL scores were indicative of the tumor-promoting activity of these cells, as exemplified by CFD, CLU, IL1R, and MS4A2 (50–59).