At admission, the median TSG-6 concentration in non-cardioembolic AIS group was 9.65 (IQR, 8.71–10.73) ng/ml and significantly higher than that of the controls [7.90 (IQR, 6.26–9.31) ng/ml; P < 0.0001; Figure 2A], suggesting that high TSG-6 level was associated with non-cardioembolic AIS. Here, TNFAIP6 is linked to androgen insensitivity syndrome.