IL4 and infection: Similarly, treatment of macrophages with IL-4/IL-13 enhanced the infection of the recombinant vesicular stomatitis virus encoding the EBOV-GP (rVSV/EBOV-GP), and a further study showed that the macrophages were polarized toward the M2a phenotype by IL-4/IL-13 with increased expression of specific intercellular adhesion molecule-3-grabbing non-integrin related gene 3 (SIGNR3), promoting the entry of rVSV/EBOV-GP into the host cells (Rogers et al., 2019).