POMC and Cushing syndrome due to macronodular adrenal hyperplasia: confirmed the diagnostic utility of hair cortisol in 43 patients with overt Cushing syndrome (26 with Cushing disease, 10 with adrenal Cushing, and 7 with ectopic ACTH secretion), reporting a sensitivity and a specificity of hair cortisol measurements for CS of 93% and 90%, respectively (22).