When controlling for duration of diabetes between the high and undetectable residual beta-cell groups, group*time interactions remained for CXCR4+ HPCs (p=0.014), CXCR7+ HPCs (p=0.030) and CXCR7+ EPCs (p=0.007), but not for HPCs (p=0.060). This evidence concerns the gene CXCR4 and diabetes mellitus.