Mutations in the α-syn-encoding gene SNCA are associated with increased risk of developing PD (Campêlo and Silva, 2017), while DJ-1 mutations give rise to a rare inherited form of PD, likely due to loss of numerous protective functions of the DJ-1 protein (Kahle et al., 2009; Giaime et al., 2010; Ariga et al., 2013). This evidence concerns the gene PARK7 and Parkinson disease.