SOD1 and amyotrophic lateral sclerosis: Altered expression of several miRNA has been observed, however, in both primary astrocytes and ADEVs from the SOD1-G93A (mSOD1) mouse model of ALS (Gomes et al., 2019, 2020), though, curiously, others found no differences in ADEV cargo between mSOD1 and wildtype mice (Jovičić and Gitler, 2017).