Finally, IL-6 exposure was found to induce both astrogliosis and a significant increase in astrocytic miR-125b-5p (Pogue et al., 2010; Table 1), a miRNA that has been associated with apoptosis, inflammation and oxidative stress that is upregulated in the AD brain (Jin et al., 2018; Figure 1A). This evidence concerns the gene IL6 and Alzheimer disease.