And, other studies reported that the level of LH in patients with PCOS had no influence on oocyte and embryo quality, as these studies did not find any difference in clinical pregnancy rate even the LH levels varied among those women (Bosch et al., 2005; Doody et al., 2010; Weiss et al., 2019). Here, PLOD1 is linked to polycystic ovary syndrome.