AGT and hypertensive disorder: Experimental data have indicated that Ang II infusion increases the number of arterial macrophages in WT mice, whereas selective ablation of lysozyme M-positive (LysM) myelomonocytic cells markedly reduces Ang II-induced hypertension, the infiltration of monocytes/macrophages and the production of superoxide in the aorta (Wenzel et al., 2011).