In the rat model of CLP-induced myocardial injury, intraperitoneal injection of resveratrol (An et al., 2016) was able to reduce myocardial injury during sepsis by decreasing neutrophil accumulation, producing the myocardial cytokine TNF-α, activating the SIRT-l pathway, reducing the production of myeloperoxidase, and suppressing cardiomyocyte apoptosis. Here, TNF is linked to Sepsis.