C5 and Decreased total leukocyte count: bFicolins-2 initiates complement cascade reactions (including C5a production) and dialysis-induced leukopenia by adsorption to polysulfone dialyzers and leads to substantial depletion of Ficolins2. MBL also activates complement reactions by contact with dialyzers (Unger et al., 2016; Flythe et al., 2020)