NEFL and Parkinson disease: Ours and other studies have indicated that some indicators such as neuroinflammatory, neuroimaging mediators and serum neurofilament light chain are usually applied as markers in diagnosing and evaluating the progression and severity of PD and PD Syndromes (Wang et al., 2020, 2021; Yang et al., 2020; Zhu et al., 2020, 2021a; Bestwick et al., 2021; Liu et al., 2021; Quadalti et al., 2021).