In the Olig2-KO mouse or Rfx3-KO (ciliopathy) mouse diencephalon, it was described as a prethalamic malformation, followed by disorganized extension of TCAs (Ono et al., 2014; Magnani et al., 2015; Andreu-Cervera et al., 2021). This evidence concerns the gene RFX3 and ciliopathy.