Moreover, scientists have demonstrated that ABZ can cause a significant decrease in the activity of hypoxia-inducible factor-Iα (HIF-1α) and vascular endothelial growth factor (VEGF) in ovarian cancer that restrains tumor angiogenesis, and as a result, decreasing the symptoms of ascites (Noorani et al., 2015[52]). This evidence concerns the gene VEGFA and neoplasm.