CCDC25 and cancer: The pro-metastatic function of NETs relies not only on their ability to trap cancer cells in circulation [111], favour their intravasation [112] and drive ECM remodelling via proteases associated with net-DNA [113,114], but even net-DNA can directly induce cancer cell invasion and proliferation via a specific receptor, the transmembrane protein CCDC25, found on cancer cells [115].