We evaluated the levels of 4‐HNE in 348 lung cancer specimens and found that the cyto‐subtype had the lowest 4‐HNE levels, while the nucl‐subtype had the highest ones (Figure 7D,E), demonstrating that lipid peroxidation is possibly dependent on RB1CC1 subcellular localisation. The gene discussed is RB1CC1; the disease is lung cancer.