In fact, in previously reported trans-ancestry GWAS meta-analyses of 180 834 T2D cases and 1 159 055 controls from the DIAMANTE Consortium (16), the lead T2D SNV is the same as we report for GDM at MTNR1B, TCF7L2 and CDKAL1, and is in strong linkage disequilibrium (LD) at the CDKN2A-CDKN2B locus (rs10811661, r2 = 0.91 across diverse populations in the 1000 Genomes Project (24)). This evidence concerns the gene CDKAL1 and type 2 diabetes mellitus.