In a single-centre study from Italy, full screening {tumour biomarkers (Ca125, CEA, Ca19.9, Ca15.3, alpha fetoprotein, prostate specific antigen), stool for occult blood, chest x-ray, abdominal ultrasound, gastroscopy, total body computed tomography (CT), colonoscopy, mammography, cervical smears and urine cytology} for cancer was performed. The gene discussed is KLK3; the disease is neoplasm.