A proportion of single B‐cells infiltrating CM express AID and BCL6 required for the formation of germinal centres (Cabrita et al., 2020); furthermore, B‐cell follicles with nucleic expression of AID are often positive for Ki67 and in close contact with melanoma, indicating cell proliferation in response to tumour is occurring (Cipponi et al., 2012). Here, AICDA is linked to melanoma.