However, chromosome 11 was found to contain the largest number of genes (ten) associated with syndromic male subfertility: H19‐ICR, KCNQ1OT1, and CDKN1C are associated with BWS, FSHB with Kallmann syndrome, RRAS2 with Noonan syndrome, BSCL2 with Congenital generalized lipodystrophy, DNAJB13 with primary ciliary dystrophy, APOA1 with testicular amyloidosis, BBS1 with BBS, and WT1 with Denys–Drash syndrome and Frasier syndrome. The gene discussed is APOA1; the disease is congenital generalized lipodystrophy.