Indeed, PTM inhibits S100 calcium-binding protein B (S100B) in glial cells through the blockage of the interaction between the S100B and p53 proteins [136]; PTM is able to exert anti-inflammatory and neuroprotective effects [137], as high expression levels of S100B have been shown to cause neuroinflammation and the progression of brain diseases [138, 139]. The gene discussed is S100B; the disease is brain disorder.