BRD4 and lung adenocarcinoma: Through a literature review, we found that RCC2 has been reported to be an oncogene and that overexpression of RCC2 induced epithelial-mesenchymal transition to promote the proliferation, invasion, and migration of lung adenocarcinoma cells; RCC2 can also be driven by BRD4 to promote the growth of esophageal squamous cell carcinoma, although this has not been reported in leukemia35–38.