Among these proteins, we focused on 10 proteins (CTSF, FBLN1, AKR1B10, CCL20, SAA1, CXCL1, CXCL3, AXL, AKR1C3, CPNE 3) based on the extent of upregulation and their close relationship with the occurrence and development of tumours reported in previous studies (Fig. 2c). This evidence concerns the gene FBLN1 and neoplasm.